TY - JOUR
T1 - Intravascular papillary endothelial heperplasia of the oral soft tissues
T2 - Report of 18 cases and review of the literature
AU - Tosios, Konstantinos
AU - Koutlas, Ioannis G.
AU - Papanicolaou, Stavros I.
PY - 1994/12
Y1 - 1994/12
N2 - Purpose: Intravascular papillary endothelial hyperplasia (IPEH) is a benign, nonneoplastic, vascular lesion, that is characterized histologically by papillary fronds lined by proliferating endothelium: it is thought to represent an unusual form of organizing thrombus. It may develop in a distended vessel or in association with other vascular lesions. The main significance of IPEH is its microscopic resemblance to angiosarcoma and possible misinterpretation as such. Methods: We report the clinicopathologic features of 18 examples of IPEH of the oral soft tissues and lips, and review such features of 55 previously reported oral cases. Results: The lips and tongue were most frequently involved and a female predilection was evident. Histologically, the pure form of IPEH was more commonly encountered. Conclusion: The differential diagnosis and possible histogenesis of the lesion are discussed.
AB - Purpose: Intravascular papillary endothelial hyperplasia (IPEH) is a benign, nonneoplastic, vascular lesion, that is characterized histologically by papillary fronds lined by proliferating endothelium: it is thought to represent an unusual form of organizing thrombus. It may develop in a distended vessel or in association with other vascular lesions. The main significance of IPEH is its microscopic resemblance to angiosarcoma and possible misinterpretation as such. Methods: We report the clinicopathologic features of 18 examples of IPEH of the oral soft tissues and lips, and review such features of 55 previously reported oral cases. Results: The lips and tongue were most frequently involved and a female predilection was evident. Histologically, the pure form of IPEH was more commonly encountered. Conclusion: The differential diagnosis and possible histogenesis of the lesion are discussed.
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U2 - 10.1016/0278-2391(94)90048-5
DO - 10.1016/0278-2391(94)90048-5
M3 - Review article
C2 - 7965329
AN - SCOPUS:0027971415
SN - 0278-2391
VL - 52
SP - 1263
EP - 1268
JO - Journal of Oral and Maxillofacial Surgery
JF - Journal of Oral and Maxillofacial Surgery
IS - 12
ER -