Abstract
Parenteral and intracerebroventricular administration of calcitonin in rats resulted in the suppression of gastric acid secretion. This suppression also occurred in rats with insulin-induced hypoglycemia and after the administration of thyrotropin-releasing hormone. Intracerebroventricularly administered calcitonin was 1000 times more effective than parenterally administered calcitonin in suppressing gastric acid secretion. Calcitonin also inhibited the development of stressinduced ulcers in rats.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 671-673 |
| Number of pages | 3 |
| Journal | Science |
| Volume | 214 |
| Issue number | 4521 |
| DOIs | |
| State | Published - 1981 |