Emerging experimental evidence show that fathers’ experiences during preconception can influence their daughters’ risk of developing breast cancer. Here we describe detailed protocols for investigation in rats and mice of paternally mediated breast cancer risk programming effects.
|Original language||English (US)|
|Title of host publication||Methods in Molecular Biology|
|Publisher||Humana Press Inc.|
|Number of pages||14|
|State||Published - 2018|
|Name||Methods in Molecular Biology|
Bibliographical noteFunding Information:
C.C.F. was a recipient of a Ph.D. scholarship from the Brazilian National Council for Scientific and Technological Development (CNPq; Proc. 153478/2012-8). T.P.O. is the recipient of a researcher fellowship from CNPq (Proc. 307910/2016-4) and is supported by grants from CNPq (Proc. 448501/2014-7), the Food Research Center (FoRC), and the São Paulo State Research Funding Agency (Proc. 2013/07914-8). S.D.A. is supported by grants from the National Institutes of Health (K22CA178309-01A1) and the American Cancer Society (Research Scholar Grant).
- Breast cancer
- Female offspring
- Mammary gland development
- Paternal programming
- Preconceptional diet