The deprotection of aromatic as well as conjugated acetals and ketals in water is catalyzed by iron(III) tosylate (1.0-5.0 mol %). Iron(III) tosylate is an inexpensive and readily available catalyst. The use of water, the most environmentally benign solvent, makes this procedure especially attractive for acetal deprotection.
Bibliographical noteFunding Information:
The authors gratefully acknowledge the funding from the National Science Foundation for a RUI (Research in Undergraduate Institutions) Grant ( # 0650682 ) awarded to R.S.M.
- Iron(III) tosylate