Is adherence to diet, physical activity, and body weight cancer prevention recommendations associated with colorectal cancer incidence in African American women?

Sarah J.O. Nomura; Chiranjeev Dash; Lynn Rosenberg; Jeffrey Yu; Julie R. Palmer; Lucile L. Adams-Campbell

doi:10.1007/s10552-016-0760-3

Is adherence to diet, physical activity, and body weight cancer prevention recommendations associated with colorectal cancer incidence in African American women?

Sarah J.O. Nomura, Chiranjeev Dash, Lynn Rosenberg, Jeffrey Yu, Julie R. Palmer, Lucile L. Adams-Campbell

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Purpose: The purpose of this study was to evaluate whether adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention recommendations was associated with colorectal cancer incidence in the Black Women’s Health Study (BWHS). Methods: In this ongoing prospective cohort of African American women (analytic cohort n = 49,103), 354 incident colorectal cancers were diagnosed between baseline (1995) and 2011. Adherence scores for seven WCRF/AICR recommendations (adherent = 1 point, non-adherent level 1 = 0.5 points, non-adherent level 2 = 0 points) were created using questionnaire data and summed to an overall adherence score (maximum = 7). Recommendation adherence and colorectal cancer incidence were evaluated using baseline and time-varying data in Cox regression models. Results: At baseline, 8.5 % of women adhered >4 recommendations. In time-varying analyses, the HR was 0.98 (95 % CI 0.84–1.15) per 0.5 point higher score and 0.51 (95 % CI 0.23–1.10) for adherence to >4 compared to <3 recommendations. Adherence to individual recommendations was not associated with colorectal cancer risk. Results were similar in models that considered baseline exposures only. Conclusions: Adherence to cancer prevention recommendations was low and not associated with colorectal cancer risk among women in the BWHS. Research in diverse populations is essential to evaluate the validity of existing recommendations, and assess whether there are alternative recommendations that are more beneficial for cancer prevention in specific populations.

Original language	English (US)
Pages (from-to)	869-879
Number of pages	11
Journal	Cancer Causes and Control
Volume	27
Issue number	7
DOIs	https://doi.org/10.1007/s10552-016-0760-3
State	Published - Jul 1 2016
Externally published	Yes

Bibliographical note

Funding Information:
S.J.O.N., L.L.A., L.R., and J.P. designed research; S.J.O.N. and J.Y. analyzed data; S.J.O.N., C.D., and L.R. wrote the paper; S.J.O.N. and L.R. had primary responsibility for final content. All authors read and approved the final manuscript. This work was supported by National Cancer Institute grants R01 CA058420 (L. Rosenberg) and UM1 CA164974 (L. Rosenberg). S.J.O.N. is supported by 5T32CA009686-19 (PI: A. Riegel). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health. Data on breast cancer pathology were obtained from several state cancer registries (AZ, CA, CO, CT, DE, DC, FL, GA, IL, IN, KY, LA, MD, MA, MI, NJ, NY, NC, OK, PA, SC, TN, TX, VA), and results reported do not necessarily represent their views. The authors are grateful to the participants and staff of the BWHS. This study was done in compliance with ethical standards with approval from the Institutional Review Board of Boston University Medical Center and informed consent was obtained from all participants.

Publisher Copyright:
© 2016, Springer International Publishing Switzerland.

Keywords

Cancer prevention
Colorectal cancer
Diet
Obesity
Physical activity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10552-016-0760-3

http://europepmc.org/articles/pmc4925173

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Cite this

@article{f6a8ba7b867d492b8fef3d1747dc52d6,

title = "Is adherence to diet, physical activity, and body weight cancer prevention recommendations associated with colorectal cancer incidence in African American women?",

abstract = "Purpose: The purpose of this study was to evaluate whether adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention recommendations was associated with colorectal cancer incidence in the Black Women{\textquoteright}s Health Study (BWHS). Methods: In this ongoing prospective cohort of African American women (analytic cohort n = 49,103), 354 incident colorectal cancers were diagnosed between baseline (1995) and 2011. Adherence scores for seven WCRF/AICR recommendations (adherent = 1 point, non-adherent level 1 = 0.5 points, non-adherent level 2 = 0 points) were created using questionnaire data and summed to an overall adherence score (maximum = 7). Recommendation adherence and colorectal cancer incidence were evaluated using baseline and time-varying data in Cox regression models. Results: At baseline, 8.5 % of women adhered >4 recommendations. In time-varying analyses, the HR was 0.98 (95 % CI 0.84–1.15) per 0.5 point higher score and 0.51 (95 % CI 0.23–1.10) for adherence to >4 compared to <3 recommendations. Adherence to individual recommendations was not associated with colorectal cancer risk. Results were similar in models that considered baseline exposures only. Conclusions: Adherence to cancer prevention recommendations was low and not associated with colorectal cancer risk among women in the BWHS. Research in diverse populations is essential to evaluate the validity of existing recommendations, and assess whether there are alternative recommendations that are more beneficial for cancer prevention in specific populations.",

keywords = "Cancer prevention, Colorectal cancer, Diet, Obesity, Physical activity",

author = "Nomura, {Sarah J.O.} and Chiranjeev Dash and Lynn Rosenberg and Jeffrey Yu and Palmer, {Julie R.} and Adams-Campbell, {Lucile L.}",

note = "Funding Information: S.J.O.N., L.L.A., L.R., and J.P. designed research; S.J.O.N. and J.Y. analyzed data; S.J.O.N., C.D., and L.R. wrote the paper; S.J.O.N. and L.R. had primary responsibility for final content. All authors read and approved the final manuscript. This work was supported by National Cancer Institute grants R01 CA058420 (L. Rosenberg) and UM1 CA164974 (L. Rosenberg). S.J.O.N. is supported by 5T32CA009686-19 (PI: A. Riegel). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health. Data on breast cancer pathology were obtained from several state cancer registries (AZ, CA, CO, CT, DE, DC, FL, GA, IL, IN, KY, LA, MD, MA, MI, NJ, NY, NC, OK, PA, SC, TN, TX, VA), and results reported do not necessarily represent their views. The authors are grateful to the participants and staff of the BWHS. This study was done in compliance with ethical standards with approval from the Institutional Review Board of Boston University Medical Center and informed consent was obtained from all participants. Publisher Copyright: {\textcopyright} 2016, Springer International Publishing Switzerland.",

year = "2016",

month = jul,

day = "1",

doi = "10.1007/s10552-016-0760-3",

language = "English (US)",

volume = "27",

pages = "869--879",

journal = "Cancer Causes and Control",

issn = "0957-5243",