Isolation and mapping, of two chicken POU family genes and the identification of a syntenic group with human and mouse

L. M. Heltemes, C. K. Tuggle, S. J. Lamont

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Two partial chicken POU domain genes were isolated by genomic library screening and reverse transcriptase-polymerase chain reaction (RT-PCR). A cDNA clone encoding the POU domain of Brn-3a, which showed near identity to the human Brn-3a sequence (100% amino acid identity), was isolated and mapped to chicken linkage group E48. A Skn-1/Epoc-1/Oct-11 genomic clone was identified and mapped to chicken linkage group E49. This mapping identified a syntenic group in chicken linkage group E49 that was conserved with human chromosome 11q23 and mouse chromosome 9.

Original languageEnglish (US)
Pages (from-to)346-350
Number of pages5
JournalAnimal Genetics
Volume28
Issue number5
DOIs
StatePublished - Oct 1997

Keywords

  • Brn-3a gene
  • Chicken
  • POU domain
  • Skn-1/Epoc-1/Oct-11 gene

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