Isolation and mapping, of two chicken POU family genes and the identification of a syntenic group with human and mouse

L. M. Heltemes; C. K. Tuggle; S. J. Lamont

doi:10.1111/j.1365-2052.1997.00160.x

Isolation and mapping, of two chicken POU family genes and the identification of a syntenic group with human and mouse

L. M. Heltemes, C. K. Tuggle, S. J. Lamont

Laboratory Medicine and Pathology

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Abstract

Two partial chicken POU domain genes were isolated by genomic library screening and reverse transcriptase-polymerase chain reaction (RT-PCR). A cDNA clone encoding the POU domain of Brn-3a, which showed near identity to the human Brn-3a sequence (100% amino acid identity), was isolated and mapped to chicken linkage group E48. A Skn-1/Epoc-1/Oct-11 genomic clone was identified and mapped to chicken linkage group E49. This mapping identified a syntenic group in chicken linkage group E49 that was conserved with human chromosome 11q23 and mouse chromosome 9.

Original language	English (US)
Pages (from-to)	346-350
Number of pages	5
Journal	Animal Genetics
Volume	28
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2052.1997.00160.x
State	Published - Oct 1997

Keywords

Brn-3a gene
Chicken
POU domain
Skn-1/Epoc-1/Oct-11 gene

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Isolation and mapping, of two chicken POU family genes and the identification of a syntenic group with human and mouse

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