Isolation and partial purification of lantana (Lantana camara L.) toxins

O. P. Sharma, R. K. Dawra, H. P.S. Makkar

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

A partially purified toxin fraction and lantadene A were obtained from Lantana camara L. leaves by batch extraction, column chromatography and fractional crystallization. Toxicity was tested in guinea pigs. The total number of chemical entities in the partially purified toxin preparation was 7, the 2 major ones being lantadene A and lantadene B. Lantadene A was nontoxic in itself. Likewise, another fraction containing lantadene A, lantadene B and 3 more components with higher polarity was found to be non-toxic. The toxic component(s) are different from lantadene A/B but appear to resemble them very closely.

Original languageEnglish (US)
Pages (from-to)165-172
Number of pages8
JournalToxicology Letters
Volume37
Issue number2
DOIs
StatePublished - Jul 1987

Keywords

  • Lantana camara
  • guinea pigs
  • hepatotoxicity
  • lantadene A
  • lantadene B
  • lantana toxins

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