Laryngeal chondrosarcoma mimicking medullary thyroid carcinoma on fine-needle aspiration cytology: A case report of a diagnostic pitfall

Shifteh Vahidi, Khalid Amin, Jimmie Stewart

Research output: Contribution to journalArticlepeer-review

Abstract

Chondrosarcoma (CS) of larynx is a rare laryngeal tumor accounting about 1% of laryngeal malignancies. When CS arises from thyroid cartilage, it may clinically present as a thyroid nodule. Here we report a rare case of CS of thyroid cartilage misinterpreted as medullary thyroid carcinoma. The main aim of this case report is to emphasize the important role of accurate clinical history, appropriate physical examination, and proper localization of the tumor and clear definitive imaging in conjunction with interpretation of cytologic smears. When any of these roles are unclear, it may result in misinterpretation of the cytologic smears. In these unusual circumstances, when cytomorphologic features does not completely fit an entity, communication with the physician and the consideration of a broad differential diagnoses in the head and neck pathology may lead to correct diagnosis and avoid diagnostic pitfalls. Also in certain conditions, ancillary studies including laboratory tests are necessary for definitive classification.

Original languageEnglish (US)
Pages (from-to)1035-1038
Number of pages4
JournalDiagnostic Cytopathology
Volume45
Issue number11
DOIs
StatePublished - Nov 2017

Keywords

  • chondrosarcoma
  • fine-needle aspiration
  • laryngeal
  • medullary carcinoma
  • thyroid

PubMed: MeSH publication types

  • Case Reports
  • Journal Article

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