Abstract
The humoral immune response and fecal shedding of Lawsonia intracellularis was investigated in 20 weanling foals following intra-rectal administration of frozen-thawed or lyophilized avirulent live L. intracellularis vaccine. Foals received either 30 mL frozen-thawed or lyophilized vaccine intra-rectally, given twice, 4 weeks apart. Serum samples from each foal were collected every 4 weeks for 16 weeks following the first vaccination and tested for anti- L. intracellularis specific IgG by immunoperoxidase monolayer assay. Rectal swabs were collected every other day following the first vaccination for 4 weeks for detection of L. intracellularis by real-time PCR. Both vaccine formulations administered intra-rectally in weanling foals were safe and led to similar onset and duration of fecal shedding and measurable serum IgG response against L. intracellularis.
Original language | English (US) |
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Pages (from-to) | 110-112 |
Number of pages | 3 |
Journal | Veterinary Journal |
Volume | 186 |
Issue number | 1 |
DOIs | |
State | Published - Oct 2010 |
Keywords
- Equine proliferative enteropathy
- Fecal shedding
- Foals
- Lawsonia intracellularis
- Serology
- Vaccine