Lessons learned from gene transfer approaches

C. H. Evans; S. C. Ghivizzani; E. R. Lechman; Z. Mi; D. Jaffurs; P. D. Robbins

doi:10.1186/ar6

Lessons learned from gene transfer approaches

C. H. Evans, S. C. Ghivizzani, E. R. Lechman, Z. Mi, D. Jaffurs, P. D. Robbins

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article reviews briefly the results of experiments in which selected genes have been transferred to the knee joints of healthy rabbits and rabbits with antigen-induced arthritis.

Original language	English (US)
Pages (from-to)	21-24
Number of pages	4
Journal	Arthritis Research
Volume	1
Issue number	1
DOIs	https://doi.org/10.1186/ar6
State	Published - 1999
Externally published	Yes

Keywords

Animal model
Cartilage
Cytokine
Gene therapy
Growth factor
Rheumatoid arthritis
Synovium

Access

10.1186/ar6

OpenUrl availability

Full text

Cite this

@article{c1b670c561db4ef9a90c8bb5ecc4c311,

title = "Lessons learned from gene transfer approaches",

abstract = "Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article reviews briefly the results of experiments in which selected genes have been transferred to the knee joints of healthy rabbits and rabbits with antigen-induced arthritis.",

keywords = "Animal model, Cartilage, Cytokine, Gene therapy, Growth factor, Rheumatoid arthritis, Synovium",

author = "Evans, {C. H.} and Ghivizzani, {S. C.} and Lechman, {E. R.} and Z. Mi and D. Jaffurs and Robbins, {P. D.}",

year = "1999",

doi = "10.1186/ar6",

language = "English (US)",

volume = "1",

pages = "21--24",

journal = "Arthritis Research",

issn = "1465-9905",

publisher = "BioMed Central",

number = "1",

}

TY - JOUR

T1 - Lessons learned from gene transfer approaches

AU - Evans, C. H.

AU - Ghivizzani, S. C.

AU - Lechman, E. R.

AU - Mi, Z.

AU - Jaffurs, D.

AU - Robbins, P. D.

PY - 1999

Y1 - 1999

N2 - Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article reviews briefly the results of experiments in which selected genes have been transferred to the knee joints of healthy rabbits and rabbits with antigen-induced arthritis.

AB - Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article reviews briefly the results of experiments in which selected genes have been transferred to the knee joints of healthy rabbits and rabbits with antigen-induced arthritis.

KW - Animal model

KW - Cartilage

KW - Cytokine

KW - Gene therapy

KW - Growth factor

KW - Rheumatoid arthritis

KW - Synovium

UR - http://www.scopus.com/inward/record.url?scp=0033281738&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033281738&partnerID=8YFLogxK

U2 - 10.1186/ar6

DO - 10.1186/ar6

M3 - Review article

C2 - 11094409

AN - SCOPUS:0033281738

SN - 1465-9905

VL - 1

SP - 21

EP - 24

JO - Arthritis Research

JF - Arthritis Research

IS - 1

ER -

Lessons learned from gene transfer approaches

Abstract

Keywords

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this