Abstract
Najt et al. identify the first-known endogenous allosteric modulator of SIRT1 and characterize a lipid droplet-nuclear signaling axis that underlies the known metabolic benefits of monounsaturated fatty acids and PLIN5.
Original language | English (US) |
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Pages (from-to) | 810-824.e8 |
Journal | Molecular Cell |
Volume | 77 |
Issue number | 4 |
DOIs | |
State | Published - Feb 20 2020 |
Bibliographical note
Publisher Copyright:© 2019 Elsevier Inc.
Keywords
- ATGL
- fatty acids
- lipid droplets
- lipolysis
- MUFA
- olive oil
- oxidative metabolism
- PGC-1α
- PLIN5
- SIRT1
PubMed: MeSH publication types
- Journal Article
- Research Support, N.I.H., Extramural
- Research Support, Non-U.S. Gov't
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