Lipo-chitooligosaccharides as regulatory signals of fungal growth and development

Tomás Allen Rush; Virginie Puech-Pagès; Adeline Bascaules; Patricia Jargeat; Fabienne Maillet; Alexandra Haouy; Arthur Quy Manh Maës; Cristobal Carrera Carriel; Devanshi Khokhani; Michelle Keller-Pearson; Joanna Tannous; Kevin R. Cope; Kevin Garcia; Junko Maeda; Chad Johnson; Bailey Kleven; Quanita J. Choudhury; Jessy Labbé; Candice Swift; Michelle A. O’Malley; Jin Woo Bok; Sylvain Cottaz; Sébastien Fort; Verena Poinsot; Michael R. Sussman; Corinne Lefort; Jeniel Nett; Nancy P. Keller; Guillaume Bécard; Jean Michel Ané

doi:10.1038/s41467-020-17615-5

Lipo-chitooligosaccharides as regulatory signals of fungal growth and development

Tomás Allen Rush, Virginie Puech-Pagès, Adeline Bascaules, Patricia Jargeat, Fabienne Maillet, Alexandra Haouy, Arthur Quy Manh Maës, Cristobal Carrera Carriel, Devanshi Khokhani, Michelle Keller-Pearson, Joanna Tannous, Kevin R. Cope, Kevin Garcia, Junko Maeda, Chad Johnson, Bailey Kleven, Quanita J. Choudhury, Jessy Labbé, Candice Swift, Michelle A. O’MalleyJin Woo Bok, Sylvain Cottaz, Sébastien Fort, Verena Poinsot, Michael R. Sussman, Corinne Lefort, Jeniel Nett, Nancy P. Keller, Guillaume Bécard, Jean Michel Ané

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Lipo-chitooligosaccharides (LCOs) are signaling molecules produced by rhizobial bacteria that trigger the nodulation process in legumes, and by some fungi that also establish symbiotic relationships with plants, notably the arbuscular and ecto mycorrhizal fungi. Here, we show that many other fungi also produce LCOs. We tested 59 species representing most fungal phyla, and found that 53 species produce LCOs that can be detected by functional assays and/or by mass spectroscopy. LCO treatment affects spore germination, branching of hyphae, pseudohyphal growth, and transcription in non-symbiotic fungi from the Ascomycete and Basidiomycete phyla. Our findings suggest that LCO production is common among fungi, and LCOs may function as signals regulating fungal growth and development.

Original language	English (US)
Article number	3897
Journal	Nature communications
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41467-020-17615-5
State	Published - Dec 1 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020, The Author(s).

Access

10.1038/s41467-020-17615-5

OpenUrl availability

Full text

Cite this

Rush, T. A., Puech-Pagès, V., Bascaules, A., Jargeat, P., Maillet, F., Haouy, A., Maës, A. Q. M., Carriel, C. C., Khokhani, D., Keller-Pearson, M., Tannous, J., Cope, K. R., Garcia, K., Maeda, J., Johnson, C., Kleven, B., Choudhury, Q. J., Labbé, J., Swift, C., ... Ané, J. M. (2020). Lipo-chitooligosaccharides as regulatory signals of fungal growth and development. Nature communications, 11(1), Article 3897. https://doi.org/10.1038/s41467-020-17615-5

Rush, TA, Puech-Pagès, V, Bascaules, A, Jargeat, P, Maillet, F, Haouy, A, Maës, AQM, Carriel, CC, Khokhani, D, Keller-Pearson, M, Tannous, J, Cope, KR, Garcia, K, Maeda, J, Johnson, C, Kleven, B, Choudhury, QJ, Labbé, J, Swift, C, O’Malley, MA, Bok, JW, Cottaz, S, Fort, S, Poinsot, V, Sussman, MR, Lefort, C, Nett, J, Keller, NP, Bécard, G & Ané, JM 2020, 'Lipo-chitooligosaccharides as regulatory signals of fungal growth and development', Nature communications, vol. 11, no. 1, 3897. https://doi.org/10.1038/s41467-020-17615-5

@article{d886c0c6e23344778da85c2c01be8253,

title = "Lipo-chitooligosaccharides as regulatory signals of fungal growth and development",

abstract = "Lipo-chitooligosaccharides (LCOs) are signaling molecules produced by rhizobial bacteria that trigger the nodulation process in legumes, and by some fungi that also establish symbiotic relationships with plants, notably the arbuscular and ecto mycorrhizal fungi. Here, we show that many other fungi also produce LCOs. We tested 59 species representing most fungal phyla, and found that 53 species produce LCOs that can be detected by functional assays and/or by mass spectroscopy. LCO treatment affects spore germination, branching of hyphae, pseudohyphal growth, and transcription in non-symbiotic fungi from the Ascomycete and Basidiomycete phyla. Our findings suggest that LCO production is common among fungi, and LCOs may function as signals regulating fungal growth and development.",

author = "Rush, {Tom{\'a}s Allen} and Virginie Puech-Pag{\`e}s and Adeline Bascaules and Patricia Jargeat and Fabienne Maillet and Alexandra Haouy and Ma{\"e}s, {Arthur Quy Manh} and Carriel, {Cristobal Carrera} and Devanshi Khokhani and Michelle Keller-Pearson and Joanna Tannous and Cope, {Kevin R.} and Kevin Garcia and Junko Maeda and Chad Johnson and Bailey Kleven and Choudhury, {Quanita J.} and Jessy Labb{\'e} and Candice Swift and O{\textquoteright}Malley, {Michelle A.} and Bok, {Jin Woo} and Sylvain Cottaz and S{\'e}bastien Fort and Verena Poinsot and Sussman, {Michael R.} and Corinne Lefort and Jeniel Nett and Keller, {Nancy P.} and Guillaume B{\'e}card and An{\'e}, {Jean Michel}",

note = "Publisher Copyright: {\textcopyright} 2020, The Author(s).",

year = "2020",

month = dec,

day = "1",

doi = "10.1038/s41467-020-17615-5",

language = "English (US)",

volume = "11",

journal = "Nature communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

number = "1",

}

TY - JOUR

T1 - Lipo-chitooligosaccharides as regulatory signals of fungal growth and development

AU - Rush, Tomás Allen

AU - Puech-Pagès, Virginie

AU - Bascaules, Adeline

AU - Jargeat, Patricia

AU - Maillet, Fabienne

AU - Haouy, Alexandra

AU - Maës, Arthur Quy Manh

AU - Carriel, Cristobal Carrera

AU - Khokhani, Devanshi

AU - Keller-Pearson, Michelle

AU - Tannous, Joanna

AU - Cope, Kevin R.

AU - Garcia, Kevin

AU - Maeda, Junko

AU - Johnson, Chad

AU - Kleven, Bailey

AU - Choudhury, Quanita J.

AU - Labbé, Jessy

AU - Swift, Candice

AU - O’Malley, Michelle A.

AU - Bok, Jin Woo

AU - Cottaz, Sylvain

AU - Fort, Sébastien

AU - Poinsot, Verena

AU - Sussman, Michael R.

AU - Lefort, Corinne

AU - Nett, Jeniel

AU - Keller, Nancy P.

AU - Bécard, Guillaume

AU - Ané, Jean Michel

PY - 2020/12/1

Y1 - 2020/12/1

N2 - Lipo-chitooligosaccharides (LCOs) are signaling molecules produced by rhizobial bacteria that trigger the nodulation process in legumes, and by some fungi that also establish symbiotic relationships with plants, notably the arbuscular and ecto mycorrhizal fungi. Here, we show that many other fungi also produce LCOs. We tested 59 species representing most fungal phyla, and found that 53 species produce LCOs that can be detected by functional assays and/or by mass spectroscopy. LCO treatment affects spore germination, branching of hyphae, pseudohyphal growth, and transcription in non-symbiotic fungi from the Ascomycete and Basidiomycete phyla. Our findings suggest that LCO production is common among fungi, and LCOs may function as signals regulating fungal growth and development.

AB - Lipo-chitooligosaccharides (LCOs) are signaling molecules produced by rhizobial bacteria that trigger the nodulation process in legumes, and by some fungi that also establish symbiotic relationships with plants, notably the arbuscular and ecto mycorrhizal fungi. Here, we show that many other fungi also produce LCOs. We tested 59 species representing most fungal phyla, and found that 53 species produce LCOs that can be detected by functional assays and/or by mass spectroscopy. LCO treatment affects spore germination, branching of hyphae, pseudohyphal growth, and transcription in non-symbiotic fungi from the Ascomycete and Basidiomycete phyla. Our findings suggest that LCO production is common among fungi, and LCOs may function as signals regulating fungal growth and development.

UR - http://www.scopus.com/inward/record.url?scp=85089068679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85089068679&partnerID=8YFLogxK

U2 - 10.1038/s41467-020-17615-5

DO - 10.1038/s41467-020-17615-5

M3 - Article

C2 - 32753587

AN - SCOPUS:85089068679

SN - 2041-1723

VL - 11

JO - Nature communications

JF - Nature communications

IS - 1

M1 - 3897

ER -

Lipo-chitooligosaccharides as regulatory signals of fungal growth and development

Abstract

Bibliographical note

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this