Localization of Prostaglandin-Forming Cyclooxygenase in Middle Ear and External Canal Tissue

Timothy T.K. Jung; S. K. Juhn; Alfred F. Michael

doi:10.1177/019459988309100214

Localization of Prostaglandin-Forming Cyclooxygenase in Middle Ear and External Canal Tissue

Timothy T.K. Jung, S. K. Juhn, Alfred F. Michael

Otolaryngology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Prostaglandins were found in the middle ear effusion and may play an important role in inflammation and bone resorption occurring in otitis media. With the use of an immunohistochemical technique, prostaglandin cyclooxygenase was localized in epithelial cells of human skin, endothelial cells of arterioles, mononuclear leukocytes and fibroblasts of human middle ear mucosa and granulation tissue, epithelial cells of chinchilla middle ear mucosa, and the external auditory canal skin.

Original language	English (US)
Pages (from-to)	187-192
Number of pages	6
Journal	Otolaryngology-Head and Neck Surgery
Volume	91
Issue number	2
DOIs	https://doi.org/10.1177/019459988309100214
State	Published - Apr 1983

Bibliographical note

Funding Information:
Supported by research grant NS 14538 from the Public Health Service and institutional fellowship 09014156 from the National Institutes of Health.

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title = "Localization of Prostaglandin-Forming Cyclooxygenase in Middle Ear and External Canal Tissue",

abstract = "Prostaglandins were found in the middle ear effusion and may play an important role in inflammation and bone resorption occurring in otitis media. With the use of an immunohistochemical technique, prostaglandin cyclooxygenase was localized in epithelial cells of human skin, endothelial cells of arterioles, mononuclear leukocytes and fibroblasts of human middle ear mucosa and granulation tissue, epithelial cells of chinchilla middle ear mucosa, and the external auditory canal skin.",

author = "Jung, {Timothy T.K.} and Juhn, {S. K.} and Michael, {Alfred F.}",

note = "Funding Information: Supported by research grant NS 14538 from the Public Health Service and institutional fellowship 09014156 from the National Institutes of Health. ",

year = "1983",

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doi = "10.1177/019459988309100214",

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AU - Michael, Alfred F.

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N2 - Prostaglandins were found in the middle ear effusion and may play an important role in inflammation and bone resorption occurring in otitis media. With the use of an immunohistochemical technique, prostaglandin cyclooxygenase was localized in epithelial cells of human skin, endothelial cells of arterioles, mononuclear leukocytes and fibroblasts of human middle ear mucosa and granulation tissue, epithelial cells of chinchilla middle ear mucosa, and the external auditory canal skin.

AB - Prostaglandins were found in the middle ear effusion and may play an important role in inflammation and bone resorption occurring in otitis media. With the use of an immunohistochemical technique, prostaglandin cyclooxygenase was localized in epithelial cells of human skin, endothelial cells of arterioles, mononuclear leukocytes and fibroblasts of human middle ear mucosa and granulation tissue, epithelial cells of chinchilla middle ear mucosa, and the external auditory canal skin.

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Localization of Prostaglandin-Forming Cyclooxygenase in Middle Ear and External Canal Tissue

Abstract

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