TY - JOUR
T1 - Long-term brain and behavioral consequences of early iron deficiency
AU - Georgieff, Michael K.
PY - 2011/11
Y1 - 2011/11
N2 - Early iron deficiency not only affects brain and behavioral function during the period of iron deficiency, it persists long after treatment. The mechanisms include long-term alterations in dopamine metabolism, myelination, and hippocampal structure and function. Recent studies have demonstrated long-term genomic changes, which suggests the regulation of brain function is fundamentally altered.
AB - Early iron deficiency not only affects brain and behavioral function during the period of iron deficiency, it persists long after treatment. The mechanisms include long-term alterations in dopamine metabolism, myelination, and hippocampal structure and function. Recent studies have demonstrated long-term genomic changes, which suggests the regulation of brain function is fundamentally altered.
KW - Early iron deficiency
KW - Long-term iron alterations
KW - Long-term iron genomic changes
UR - http://www.scopus.com/inward/record.url?scp=80155160039&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80155160039&partnerID=8YFLogxK
U2 - 10.1111/j.1753-4887.2011.00432.x
DO - 10.1111/j.1753-4887.2011.00432.x
M3 - Article
C2 - 22043882
AN - SCOPUS:80155160039
SN - 0029-6643
VL - 69
SP - S43-S48
JO - Nutrition reviews
JF - Nutrition reviews
IS - SUPPL. 1
ER -