Longitudinal compliance with annual screening for fecal occult blood

William Thomas, Christine M. White, Jeng Mah, Mindy S. Geisser, Timothy R. Church, Jack S. Mandel

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


In a randomized, controlled trial of fecal occult blood screening for colorectal cancer, the Minnesota Colon Cancer Control Study carried out 11 annual mail screens in two phases between 1976 and 1992. This long-term compliance record of 15,476 individuals is summarized and related to demographic characteristics as well as to the screening experience of the participants. There was a strong and consistent effect of age, with peak compliance among participants about 70 years old, and lower compliance among the youngest (≤55 years) and oldest (≥80 years) participants. There was a significantly higher rate of screen compliance among participants who lived with other participants, compared with households where only one individual participated in the study. Finally, participants who underwent a diagnostic colorectal examination with negative results had significantly lower odds of compliance.

Original languageEnglish (US)
Pages (from-to)176-182
Number of pages7
JournalAmerican journal of epidemiology
Issue number2
StatePublished - Jul 15 1995

Bibliographical note

Funding Information:
Supported by research contract nos. NIH/NO1-CB-95613, NO1-CB-61005, and NO1-CB-53862 with the National Cancer Institute.


  • Colonic neoplasms
  • Cooperative behavior
  • Mass screening
  • Prospective studies


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