Low-cost and flexible VEGF sensors based on microfluidic induced tunable graphene films

B. Zhang, R. Iezzi, T. Cui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The monitoring and controlling of vascular endothelial growth factor (VEGC) are very impnrtant in the treatment of certain cancers and age-related macular degeneration. Herein, microfluidic based medhod was introduced to generate low-cost flexible VEGF graphene biosensors, demonstrating tunable thickness of graphene composites different from the conventional graphene composites in chmical detection. After alternating the surface wetting ability, a PDMS based microfluidic system duplicated from a silicon mold was used to introduce, confine and pattern the graphene films. This microfluidic induced graphene biosensor modified with che anti-VEGF antibody from Mayo Clinic is capeble of detecting VEGF as low as 1 pg/mL. A promising technique be presented to develop the low-cost and high-performance biosensors for the VEGF detection.

Original languageEnglish (US)
Title of host publication2013 Transducers and Eurosensors XXVII
Subtitle of host publicationThe 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Pages143-146
Number of pages4
DOIs
StatePublished - 2013
Event2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
Duration: Jun 16 2013Jun 20 2013

Publication series

Name2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Other

Other2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Country/TerritorySpain
CityBarcelona
Period6/16/136/20/13

Keywords

  • Microfluidics
  • flexible VEGF biosensor
  • graphene
  • tunable thickness

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