Major depression in unexplained infertility

W. Meller, L. H. Burns, S. Crow, P. Grambsch

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Although a potential relationship between depression and infertility has been described throughout history, only recently has this topic been subjected to systematic investigation, and the literature is often confusing. The present study uses well-established structured psychiatric interviews - Structured Clinical Interview for DSM-III-R (SCID), Beck and Family History-Research Diagnostic Criteria (Fh-RDC) - to investigate the prevalence of major depression in a small group of women with infertility of unknown origin, and a community control sample. There were significantly more women with current depression or a history of depression in the infertile group, and of these women the majority experienced their depressive episode prior to their diagnosis of infertility.

Original languageEnglish (US)
Pages (from-to)27-30
Number of pages4
JournalJournal of Psychosomatic Obstetrics and Gynecology
Issue number1
StatePublished - Jan 1 2002


  • Depression
  • Infertility
  • Unexplained
  • Unknown origin

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