Major groove orientation of the (2S)-N⁶-(2-hydroxy-3-buten-1-yl)-2′-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene

Medicine & Life Sciences

• butylene 69%
• 1,3-butadiene 51%
• DNA Adducts 50%
• Adenine 20%
• Base Pairing 17%
• Carbon 16%
• Hydroxyl Radical 12%
• Direction compound 12%
• Thymine 7%
• Alkylation 7%
• Hydrogen Bonding 6%
• Guanine 6%
• Mixed Function Oxygenases 6%
• Nucleosides 6%
• Protons 5%
• Codon 5%
• Nitrogen 5%
• Cytochrome P-450 Enzyme System 5%
• Carcinogens 5%
• Magnetic Resonance Spectroscopy 4%
• Carcinogenesis 4%
• Mutation 3%
• DNA 3%

Chemical Compounds

• Adduct 28%
• Adenine 18%
• Genotoxicity 16%
• Butene 12%
• Carbon Atom 9%
• Nucleobase 7%
• Cytochrome P450 7%
• Thymine 7%
• Butadiene 6%
• Guanine 6%
• Nucleoside 6%
• Alkylation 5%
• Mutation 5%
• NMR Spectroscopy 4%
• Proton 4%
• Hydrogen Bond 4%
• Nitrogen 4%
• Solvent 3%
• Reduction 3%