Malignant histiocytosis in a patient presenting with leukocytosis, eosinophilia, and lymph node granuloma

James O. Ballard; Richard A. Binder; Charles E. Rath; Deborah Powell

doi:10.1002/1097-0142(197505)35:5<1444::AID-CNCR2820350531>3.0.CO;2-Y

Malignant histiocytosis in a patient presenting with leukocytosis, eosinophilia, and lymph node granuloma

James O. Ballard, Richard A. Binder, Charles E. Rath, Deborah Powell

Laboratory Medicine and Pathology

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Abstract

A patient with malignant histiocytosis presented with a number of unusual features including fever, leukemoid reaction, and eosinophilia. Other confusing findings included lymph node biopsies which showed reactive changes, noncaseating granuloma, and atypical Reed‐Sternberg cells. These features are compared with cases appearing in the literature. The course was rapidly progressive despite combination chemotherapy.

Original language	English (US)
Pages (from-to)	1444-1448
Number of pages	5
Journal	Cancer
Volume	35
Issue number	5
DOIs	https://doi.org/10.1002/1097-0142(197505)35:5<1444::AID-CNCR2820350531>3.0.CO;2-Y
State	Published - May 1975

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abstract = "A patient with malignant histiocytosis presented with a number of unusual features including fever, leukemoid reaction, and eosinophilia. Other confusing findings included lymph node biopsies which showed reactive changes, noncaseating granuloma, and atypical Reed‐Sternberg cells. These features are compared with cases appearing in the literature. The course was rapidly progressive despite combination chemotherapy.",

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AB - A patient with malignant histiocytosis presented with a number of unusual features including fever, leukemoid reaction, and eosinophilia. Other confusing findings included lymph node biopsies which showed reactive changes, noncaseating granuloma, and atypical Reed‐Sternberg cells. These features are compared with cases appearing in the literature. The course was rapidly progressive despite combination chemotherapy.

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Malignant histiocytosis in a patient presenting with leukocytosis, eosinophilia, and lymph node granuloma

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