Malignant peripheral nerve sheath tumour in a sow

Talita P. Resende, Carlos E.R. Pereira, Fabio A. Vannucci, Fernando S. Araujo, José Lúcio Santos, Geovanni D. Cassali, Karine A. Damasceno, Roberto M.C. Guedes

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Nodular lung lesions in swine are frequently due to abscesses or granulomatous pneumonia. Although tumours are rarely reported in modern pig farming, they should be considered as a differential diagnosis when nodular lung lesions are found. A first-parity sow exhibiting respiratory signs was euthanized. Several whitish firm nodules, not encapsulated, ranging in diameter from 0.5 to 5cm were present in all lung lobes. Microscopically, the nodules were composed of dense neoplastic cells, mainly in Antoni types A and B patterns, infiltrative and with development of emboli. All neoplastic cells stained positively by immunohistochemistry for vimentin and S-100 protein, with variable immunostaining for glial fibrillary acidic protein and stained negative for cytokeratin. Based on the gross, histological and immunohistochemical features, the tumor was diagnosed as malignant peripheral nerve sheath tumour.

Original languageEnglish (US)
Article number56
JournalActa veterinaria Scandinavica
Volume57
Issue number1
DOIs
StatePublished - Sep 25 2015

Bibliographical note

Publisher Copyright:
© 2015 Resende et al.

Keywords

  • Lung
  • Peripheral nerve sheath tumor
  • Schwannoma
  • Swine

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