TY - JOUR
T1 - Malignant peripheral nerve sheath tumour in a sow
AU - Resende, Talita P.
AU - Pereira, Carlos E.R.
AU - Vannucci, Fabio A.
AU - Araujo, Fernando S.
AU - Santos, José Lúcio
AU - Cassali, Geovanni D.
AU - Damasceno, Karine A.
AU - Guedes, Roberto M.C.
N1 - Publisher Copyright:
© 2015 Resende et al.
PY - 2015/9/25
Y1 - 2015/9/25
N2 - Nodular lung lesions in swine are frequently due to abscesses or granulomatous pneumonia. Although tumours are rarely reported in modern pig farming, they should be considered as a differential diagnosis when nodular lung lesions are found. A first-parity sow exhibiting respiratory signs was euthanized. Several whitish firm nodules, not encapsulated, ranging in diameter from 0.5 to 5cm were present in all lung lobes. Microscopically, the nodules were composed of dense neoplastic cells, mainly in Antoni types A and B patterns, infiltrative and with development of emboli. All neoplastic cells stained positively by immunohistochemistry for vimentin and S-100 protein, with variable immunostaining for glial fibrillary acidic protein and stained negative for cytokeratin. Based on the gross, histological and immunohistochemical features, the tumor was diagnosed as malignant peripheral nerve sheath tumour.
AB - Nodular lung lesions in swine are frequently due to abscesses or granulomatous pneumonia. Although tumours are rarely reported in modern pig farming, they should be considered as a differential diagnosis when nodular lung lesions are found. A first-parity sow exhibiting respiratory signs was euthanized. Several whitish firm nodules, not encapsulated, ranging in diameter from 0.5 to 5cm were present in all lung lobes. Microscopically, the nodules were composed of dense neoplastic cells, mainly in Antoni types A and B patterns, infiltrative and with development of emboli. All neoplastic cells stained positively by immunohistochemistry for vimentin and S-100 protein, with variable immunostaining for glial fibrillary acidic protein and stained negative for cytokeratin. Based on the gross, histological and immunohistochemical features, the tumor was diagnosed as malignant peripheral nerve sheath tumour.
KW - Lung
KW - Peripheral nerve sheath tumor
KW - Schwannoma
KW - Swine
UR - http://www.scopus.com/inward/record.url?scp=84942328601&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84942328601&partnerID=8YFLogxK
U2 - 10.1186/s13028-015-0150-y
DO - 10.1186/s13028-015-0150-y
M3 - Article
C2 - 26407677
AN - SCOPUS:84942328601
SN - 0044-605X
VL - 57
JO - Acta veterinaria Scandinavica
JF - Acta veterinaria Scandinavica
IS - 1
M1 - 56
ER -
