TY - JOUR
T1 - Management of cardiogenic shock complicating myocardial infarction
AU - Mebazaa, Alexandre
AU - Combes, Alain
AU - van Diepen, Sean
AU - Hollinger, Alexa
AU - Katz, Jaon N.
AU - Landoni, Giovanni
AU - Hajjar, Ludhmila Abrahao
AU - Lassus, Johan
AU - Lebreton, Guillaume
AU - Montalescot, Gilles
AU - Park, Jin Joo
AU - Price, Susanna
AU - Sionis, Alessandro
AU - Yannopolos, Demetris
AU - Harjola, Veli Pekka
AU - Levy, Bruno
AU - Thiele, Holger
N1 - Publisher Copyright:
© 2018, Springer-Verlag GmbH Germany, part of Springer Nature and ESICM.
PY - 2018/6/1
Y1 - 2018/6/1
N2 - Up to 10% of acute coronary syndromes are complicated by cardiogenic shock (CS) with contemporary mortality rates of 40–50%. The extent of ischemic myocardium has a profound impact on the initial, in-hospital, and post-discharge management and prognosis in this patient population. Individualized patient risk assessment plays an important role in determining appropriate revascularization, drug treatment with inotropes and vasopressors, mechanical circulatory support, intensive care support of other organ systems, hospital level of care triage, and allocation of clinical resources. This review will outline the underlying causes and diagnostic criteria, pathophysiology, and treatment of CS complicating acute coronary syndromes with a focus on (a) potential therapeutic issues from the perspective an interventional cardiologist, an emergency physician, and an intensive care physician, (b) the type of revascularization, and (c) new therapeutic advancements in pharmacologic and mechanical percutaneous circulatory support.
AB - Up to 10% of acute coronary syndromes are complicated by cardiogenic shock (CS) with contemporary mortality rates of 40–50%. The extent of ischemic myocardium has a profound impact on the initial, in-hospital, and post-discharge management and prognosis in this patient population. Individualized patient risk assessment plays an important role in determining appropriate revascularization, drug treatment with inotropes and vasopressors, mechanical circulatory support, intensive care support of other organ systems, hospital level of care triage, and allocation of clinical resources. This review will outline the underlying causes and diagnostic criteria, pathophysiology, and treatment of CS complicating acute coronary syndromes with a focus on (a) potential therapeutic issues from the perspective an interventional cardiologist, an emergency physician, and an intensive care physician, (b) the type of revascularization, and (c) new therapeutic advancements in pharmacologic and mechanical percutaneous circulatory support.
KW - Acute myocardial infarction
KW - Cardiogenic shock
KW - Catecholamines
KW - Mechanical circulatory support
UR - http://www.scopus.com/inward/record.url?scp=85047150371&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047150371&partnerID=8YFLogxK
U2 - 10.1007/s00134-018-5214-9
DO - 10.1007/s00134-018-5214-9
M3 - Review article
C2 - 29767322
AN - SCOPUS:85047150371
SN - 0342-4642
VL - 44
SP - 760
EP - 773
JO - Intensive Care Medicine
JF - Intensive Care Medicine
IS - 6
ER -