Mania following addition of hydroxytryptophan to monoamine oxidase inhibitor

José V. Pardo

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


This case report highlights the risk of nutritional supplements and misinformation obtained from the internet particularly for those on monamine oxdiase inhibitors (MAOIs). Despite sophisticated medical knowledge, this patient, who was taking an MOAI and complying with a tyramine-free diet, used a supplement of hydroxytryptophan that along with the MAOI appears to have precipitated mania, despite no personal or familial history of bipolar disorder.

Original languageEnglish (US)
Pages (from-to)102.e13-102.e14
JournalGeneral Hospital Psychiatry
Issue number1
StatePublished - Jan 2012

Bibliographical note

Copyright 2018 Elsevier B.V., All rights reserved.


  • Hydroxytryptophan
  • Internet
  • Mania
  • Monamine oxidase inhibitor (MAOI)
  • Serotonin syndrome


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