Mapping of lateral geniculate nucleus activation during visual stimulation in human brain using fMRI

Wei Chen; Toshinori Kato; Xiao-Hong Zhu; John Strupp; Seiji Ogawa; Kamil Ugurbil

doi:10.1002/mrm.1910390115

Mapping of lateral geniculate nucleus activation during visual stimulation in human brain using fMRI

Wei Chen, Toshinori Kato, Xiao-Hong Zhu, John Strupp, Seiji Ogawa, Kamil Ugurbil

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Abstract

Functional magnetic resonance imaging has been successfully used to map the activation in the lateral geniculate nucleus (LGN) in both hemispheres as well as the primary visual cortex (V1) during a checkerboard visual stimulation. The average blood oxygenation level dependent (BOLD) change in LGN was less than that in V1. However, the BOLD temporal responses were similar between LGN and V1. The activation in the pulvinar nucleus during visual perception was also detected, and its activated location could be separated from LGN in 3D images. The LGN activation between intersubject and intrasubject multiple trials was compared. The results demonstrate that fMRI can reliably and robustly detect small subcortical nucleus activation in the human brain.

Original language	English (US)
Pages (from-to)	89-96
Number of pages	8
Journal	Magnetic resonance in medicine
Volume	39
Issue number	1
DOIs	https://doi.org/10.1002/mrm.1910390115
State	Published - Jan 1998

Keywords

FMRI
Lateral geniculate nucleus
Primary visual cortex
Pulvinar
Visual stimulation

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abstract = "Functional magnetic resonance imaging has been successfully used to map the activation in the lateral geniculate nucleus (LGN) in both hemispheres as well as the primary visual cortex (V1) during a checkerboard visual stimulation. The average blood oxygenation level dependent (BOLD) change in LGN was less than that in V1. However, the BOLD temporal responses were similar between LGN and V1. The activation in the pulvinar nucleus during visual perception was also detected, and its activated location could be separated from LGN in 3D images. The LGN activation between intersubject and intrasubject multiple trials was compared. The results demonstrate that fMRI can reliably and robustly detect small subcortical nucleus activation in the human brain.",

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AU - Ugurbil, Kamil

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Mapping of lateral geniculate nucleus activation during visual stimulation in human brain using fMRI

Abstract

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