Abstract
The observation that 125I-labeled polysomal mRNA is located in lightly staining regions confirms the previous finding with cDNA transcribed from total cytoplasmic poly(A+) RNA and strongly suggests that genes present in low multiplicity copies are primarily located in G-negative rather than G-positive bands. This should serve as a useful guide in the mapping of individual genes to specific chromosomal bands. The finding that reiterated large-molecular-weight nuclear RNA sequence transcripts are also localized in lightly staining regions supports the suggestion that mRNA and HnRNA originate from related DNA sequences.
Original language | English (US) |
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Pages (from-to) | 364-367 |
Number of pages | 4 |
Journal | Cytogenetics and Cell Genetics |
Volume | 22 |
Issue number | 1 |
DOIs | |
State | Published - 1978 |