Mass spectrometry: An emerging alternative to traditional methods for measurement of diagnostic proteins, peptides and amino acids

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Abstract

Novel approaches to protein measurement based on mass spectrometry are being developed that challenge more traditional methods. This review summarizes the emergence of mass spectrometry as a tool for clinical protein, peptide, and amino acid determination. Specific applications of mass spectrometry to the measurement of transferrin, transthyretin, glycated hemoglobin, and homocysteine will be discussed, as will the limitations of the technology, and future directions for clinical protein measurement.

Original languageEnglish (US)
Pages (from-to)181-190
Number of pages10
JournalCurrent Protein and Peptide Science
Volume3
Issue number2
DOIs
StatePublished - Jan 1 2002

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