Mathematical models in biology: From molecules to life

Yiannis N. Kaznessis

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


A vexing question in the biological sciences is the following: can biological phenotypes be explained with mathematical models of molecules that interact according to physical laws? At the crux of the matter lies the doubt that humans can develop physically faithful mathematical representations of living organisms. We discuss advantages that synthetic biological systems confer that may help us describe life's distinctiveness with tractable mathematics that are grounded on universal laws of thermodynamics and molecular biology.

Original languageEnglish (US)
Pages (from-to)314-322
Number of pages9
JournalWiley Interdisciplinary Reviews: Systems Biology and Medicine
Issue number3
StatePublished - May 2011


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