Abstract
A study was carried out to quantify simultaneously fibroblast migration and traction. Tissue-equivalent (TE) cylinders were prepared from collagen and human foreskin fibroblast. Compaction of attached and floating TE cylinders were measured and fit with a model. The mechanical stress developed in the attached TE cylinders caused an increase in fibroblast traction but a decrease in migration as compared to floating stress-free TE cylinders, indicating a complex mechanotransduction effect on cell motility.
Original language | English (US) |
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Title of host publication | American Society of Mechanical Engineers, Bioengineering Division (Publication) BED |
Publisher | ASME |
Pages | 617-618 |
Number of pages | 2 |
Volume | 42 |
ISBN (Print) | 0791816117 |
State | Published - 1999 |
Event | 1999 Bioengineering Conference - Big Sky, MT, USA Duration: Jun 16 1999 → Jun 20 1999 |
Other
Other | 1999 Bioengineering Conference |
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City | Big Sky, MT, USA |
Period | 6/16/99 → 6/20/99 |