Mechanisms and management of bone cancer pain

Patrick W. O'Donnell; Denis R. Clohisy

doi:10.1016/B978-0-12-416721-6.00047-9

Mechanisms and management of bone cancer pain

Patrick W. O'Donnell, Denis R. Clohisy

Orthopaedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Bone cancer pain is a multifactorial process with many potential targets for therapeutic intervention. As pain is the most common presenting symptom in patients with skeletal metastases and is directly proportional to the patient's quality of life, clinical improvements in the treatment of bone cancer pain are of the utmost importance. Research targeting pain-related cytokines, anti-osteoclastic medications, and ion channels have shown significant clinical progress in the treatment of cancer-related bone pain. With continued efforts into these and other therapeutic strategies, we hope to continue to improve the quality of life of those patients suffering with bone cancer pain.

Original language	English (US)
Title of host publication	Bone Cancer
Subtitle of host publication	Primary Bone Cancers and Bone Metastases: Second Edition
Publisher	Elsevier Inc.
Pages	571-577
Number of pages	7
ISBN (Electronic)	9780124167285
ISBN (Print)	9780124167216
DOIs	https://doi.org/10.1016/B978-0-12-416721-6.00047-9
State	Published - 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc. All rights reserved..

Keywords

Bone cancer
Pain
Skeletal mestastasis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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AB - Bone cancer pain is a multifactorial process with many potential targets for therapeutic intervention. As pain is the most common presenting symptom in patients with skeletal metastases and is directly proportional to the patient's quality of life, clinical improvements in the treatment of bone cancer pain are of the utmost importance. Research targeting pain-related cytokines, anti-osteoclastic medications, and ion channels have shown significant clinical progress in the treatment of cancer-related bone pain. With continued efforts into these and other therapeutic strategies, we hope to continue to improve the quality of life of those patients suffering with bone cancer pain.

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KW - Skeletal mestastasis

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ER -

Mechanisms and management of bone cancer pain

Abstract

Bibliographical note

Keywords

UN SDGs

Access

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