Mechanisms behind estrogen's beneficial effect on muscle strength in females

Dawn A. Lowe; Kristen A. Baltgalvis; Sarah M. Greising

doi:10.1097/JES.0b013e3181d496bc

Mechanisms behind estrogen's beneficial effect on muscle strength in females

Dawn A. Lowe, Kristen A. Baltgalvis, Sarah M. Greising

Research output: Contribution to journal › Article › peer-review

131 Scopus citations

Abstract

Muscle weakness ensues when serum testosterone declines with age in men. Testosterone's female counterpart, estrogen, also has been implicated in age-related strength loss, but these results are less conclusive. Our working hypothesis is that estrogens do benefit muscle strength, and that the underlying mechanism involves estrogen receptors to improve muscle quality more so than quantity.

Original language	English (US)
Pages (from-to)	61-67
Number of pages	7
Journal	Exercise and sport sciences reviews
Volume	38
Issue number	2
DOIs	https://doi.org/10.1097/JES.0b013e3181d496bc
State	Published - Apr 2010

Keywords

17A-estradiol
Aging
Estrogen receptor
Hormone replacement therapy
Myosin
Skeletal muscle

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title = "Mechanisms behind estrogen's beneficial effect on muscle strength in females",

abstract = "Muscle weakness ensues when serum testosterone declines with age in men. Testosterone's female counterpart, estrogen, also has been implicated in age-related strength loss, but these results are less conclusive. Our working hypothesis is that estrogens do benefit muscle strength, and that the underlying mechanism involves estrogen receptors to improve muscle quality more so than quantity.",

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AU - Baltgalvis, Kristen A.

AU - Greising, Sarah M.

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AB - Muscle weakness ensues when serum testosterone declines with age in men. Testosterone's female counterpart, estrogen, also has been implicated in age-related strength loss, but these results are less conclusive. Our working hypothesis is that estrogens do benefit muscle strength, and that the underlying mechanism involves estrogen receptors to improve muscle quality more so than quantity.

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KW - Aging

KW - Estrogen receptor

KW - Hormone replacement therapy

KW - Myosin

KW - Skeletal muscle

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Mechanisms behind estrogen's beneficial effect on muscle strength in females

Abstract

Keywords

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