Medical outcomes of adolescent live kidney donors

David Macdonald, Aleksandra K. Kukla, Sarah Ake, Danielle Berglund, Scott Jackson, Naim Issa, Richard Spong, Arthur J. Matas, Hassan N. Ibrahim

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Living kidney donation from donors <18 yr of age is uncommon. The majority of donations from adolescents took place several decades ago providing a unique opportunity to study true long-term consequences of donation. We compared survival, renal outcomes, and rates of hypertension and diabetes among 42 adolescent donors and matched older controls. Adolescent donors were matched with donors 18-30 yr on the following: gender, relation to the recipient, BMI at donation, eGFR at donation, and year of donation. After a mean follow-up of 31.8 ± 8.0 yr, 94.9% of adolescent donors were alive vs. 93.8% of controls. There was no significant difference in having eGFR (MDRD) <60 mL/min/1.73 m2 (26.1% vs. 40.9%), hypertension (35.9% vs. 39.4%), diabetes (5.1% vs. 12.5%), or proteinuria (15.4% vs. 14.1%): adolescent donors vs. controls for all comparisons. These data suggest that adolescent donors are not at a higher risk of shortened survival, hypertension, diabetes, or proteinuria. Nevertheless, they probably should donate only when other options are exhausted as they have to live with a single kidney for decades and longer follow-up is needed.

Original languageEnglish (US)
Pages (from-to)336-341
Number of pages6
JournalPediatric transplantation
Volume18
Issue number4
DOIs
StatePublished - Jun 2014

Keywords

  • adolescent
  • diabetes mellitus
  • donor
  • glomerular filtration rate
  • hypertension
  • kidney
  • proteinuria

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