Melan-A/Mart-1- or HMB-45-positive melanocytes are not present in calcifying cystic odontogenic tumors (calcifying odontogenic cysts): a study in 13 Caucasian patients.

Konstantinos I. Tosios, Nikolaos Prountzos, Nikolaos Katsoulas, Ioannis G. Koutlas, Alexandra Sklavounou-Andrikopoulou

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Abstract

Melanin pigment and melanocytes may be found in odontogenic cysts and tumors, particularly calcifying cystic odontogenic tumor (CCOT). In the present study we investigated the immunohistochemical expression of the Melan-A/Mart-1 and HMB-45 antigens in 13 Caucasians patients with CCOT. Melan-A/Mart-1- and HMB-45-positive melanocytes were not seen in any of the cases. Our findings are in agreement with the assumption that pigmentation in odontogenic lesions may be a racial phenomenon.

Original languageEnglish (US)
Pages (from-to)33-38
Number of pages6
JournalJournal of Oral Science
Volume54
Issue number1
DOIs
StatePublished - Mar 2012

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