Methods and design of the Chennai Glaucoma Study

Hemamalini Arvind; Pradeep G. Paul; Prema Raju; M. Baskaran; Ronnie George; Sukumar Balu; Sarangapani Sripriya; S. Ve Ramesh; Bickol N. Mukesh; Lingam Vijaya; Govindasamy Kumaramanickavel; Catherine McCarty

doi:10.1076/opep.10.5.337.17320

Methods and design of the Chennai Glaucoma Study

Hemamalini Arvind, Pradeep G. Paul, Prema Raju, M. Baskaran, Ronnie George, Sukumar Balu, Sarangapani Sripriya, S. Ve Ramesh, Bickol N. Mukesh, Lingam Vijaya, Govindasamy Kumaramanickavel, Catherine McCarty

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Abstract

PURPOSE: To describe the methodology of a population-based study to estimate the prevalence of glaucoma in a rural and urban South Indian population and to study the genetics of glaucoma in this population. METHODS: A sample size of 4758 each for rural and urban populations in the Indian state of Tamil Nadu was calculated. Eligible subjects aged 40 years and above from the rural study area covering 32 contiguous villages and the urban area comprising five random clusters in Chennai city are enumerated. Demographic data are collected in the field. A detailed clinical examination, including glaucoma diagnostic procedures, is conducted at the examination centre. Pedigree ascertainment and genetic studies are performed for subjects with occludable angles or glaucoma. Data are recorded in a computerised database. CONCLUSIONS: This study is expected to result in an estimation of the prevalence and a better understanding of the genetics of glaucoma in this region.

Original language	English (US)
Pages (from-to)	337-348
Number of pages	12
Journal	Ophthalmic Epidemiology
Volume	10
Issue number	5
DOIs	https://doi.org/10.1076/opep.10.5.337.17320
State	Published - Dec 2003

Bibliographical note

Funding Information:
The authors would like to thank the Chennai Willingdon Corporate Foundation for their financial support, in part to this project.

Keywords

Genetics
Glaucoma epidemiology
Glaucoma prevalence
India
Population-based studies

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AU - Arvind, Hemamalini

AU - Paul, Pradeep G.

AU - Raju, Prema

AU - Baskaran, M.

AU - George, Ronnie

AU - Balu, Sukumar

AU - Sripriya, Sarangapani

AU - Ve Ramesh, S.

AU - Mukesh, Bickol N.

AU - Vijaya, Lingam

AU - Kumaramanickavel, Govindasamy

AU - McCarty, Catherine

N1 - Funding Information: The authors would like to thank the Chennai Willingdon Corporate Foundation for their financial support, in part to this project.

PY - 2003/12

Y1 - 2003/12

N2 - PURPOSE: To describe the methodology of a population-based study to estimate the prevalence of glaucoma in a rural and urban South Indian population and to study the genetics of glaucoma in this population. METHODS: A sample size of 4758 each for rural and urban populations in the Indian state of Tamil Nadu was calculated. Eligible subjects aged 40 years and above from the rural study area covering 32 contiguous villages and the urban area comprising five random clusters in Chennai city are enumerated. Demographic data are collected in the field. A detailed clinical examination, including glaucoma diagnostic procedures, is conducted at the examination centre. Pedigree ascertainment and genetic studies are performed for subjects with occludable angles or glaucoma. Data are recorded in a computerised database. CONCLUSIONS: This study is expected to result in an estimation of the prevalence and a better understanding of the genetics of glaucoma in this region.

AB - PURPOSE: To describe the methodology of a population-based study to estimate the prevalence of glaucoma in a rural and urban South Indian population and to study the genetics of glaucoma in this population. METHODS: A sample size of 4758 each for rural and urban populations in the Indian state of Tamil Nadu was calculated. Eligible subjects aged 40 years and above from the rural study area covering 32 contiguous villages and the urban area comprising five random clusters in Chennai city are enumerated. Demographic data are collected in the field. A detailed clinical examination, including glaucoma diagnostic procedures, is conducted at the examination centre. Pedigree ascertainment and genetic studies are performed for subjects with occludable angles or glaucoma. Data are recorded in a computerised database. CONCLUSIONS: This study is expected to result in an estimation of the prevalence and a better understanding of the genetics of glaucoma in this region.

KW - Genetics

KW - Glaucoma epidemiology

KW - Glaucoma prevalence

KW - India

KW - Population-based studies

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Methods and design of the Chennai Glaucoma Study

Abstract

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Keywords

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