MicroRNAs have emerged as novel and important regulators of translation. Besides their biological significance, they are being investigated as potential biomarkers of physiological and pathological states. This review article summarizes current investigations of microRNAs as biomarkers in lung cancer. The promises and pitfalls of this exciting new investigational avenue are highlighted.
Bibliographical noteFunding Information:
Supported by research grants from the Buswell Foundation and the Thoracic Surgery Foundation for Research and Education , and by a Young Investigator Award from the Cancer and Leukemia Group B (CALGB) Foundation. Research support was also received from the Medical Prognosis Institute , Horsholm, Denmark.
Copyright 2018 Elsevier B.V., All rights reserved.
- computed tomography
- formalin-fixed paraffin-embedded
- real-time polymerase chain reaction
- red blood cell