Microwave-assisted Suzuki-Miyaura couplings on α-iodoenaminones

Xin Wang, Brandon J. Turunen, Matthew W. Leighty, Gunda I. Georg

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

A systematic study of α-iodination and subsequent Suzuki-Miyaura couplings between non-attenuated enaminones and a wide range of aromatic boronic acids is reported. The microwave-assisted variant of this transformation furnished the α-arylenaminones in significantly shorter reaction times and slightly improved yields as compared to conventional heating.

Original languageEnglish (US)
Pages (from-to)8811-8814
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number50
DOIs
StatePublished - Dec 10 2007
Externally publishedYes

Bibliographical note

Funding Information:
We thank the National Institutes of Health for their generous support of our programs (NIH CA90602, NIH GM076302, and NIH GM069663). B.J.T. was supported by the Department of Defense Breast Cancer Predoctoral Fellowship (DAMD17-02-1-0435).

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