Microwave-assisted Suzuki-Miyaura couplings on α-iodoenaminones

Xin Wang; Brandon J. Turunen; Matthew W. Leighty; Gunda I. Georg

doi:10.1016/j.tetlet.2007.10.078

Microwave-assisted Suzuki-Miyaura couplings on α-iodoenaminones

Xin Wang, Brandon J. Turunen, Matthew W. Leighty, Gunda I. Georg

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

A systematic study of α-iodination and subsequent Suzuki-Miyaura couplings between non-attenuated enaminones and a wide range of aromatic boronic acids is reported. The microwave-assisted variant of this transformation furnished the α-arylenaminones in significantly shorter reaction times and slightly improved yields as compared to conventional heating.

Original language	English (US)
Pages (from-to)	8811-8814
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
Issue number	50
DOIs	https://doi.org/10.1016/j.tetlet.2007.10.078
State	Published - Dec 10 2007
Externally published	Yes

Bibliographical note

Funding Information:
We thank the National Institutes of Health for their generous support of our programs (NIH CA90602, NIH GM076302, and NIH GM069663). B.J.T. was supported by the Department of Defense Breast Cancer Predoctoral Fellowship (DAMD17-02-1-0435).

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abstract = "A systematic study of α-iodination and subsequent Suzuki-Miyaura couplings between non-attenuated enaminones and a wide range of aromatic boronic acids is reported. The microwave-assisted variant of this transformation furnished the α-arylenaminones in significantly shorter reaction times and slightly improved yields as compared to conventional heating.",

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AU - Wang, Xin

AU - Turunen, Brandon J.

AU - Leighty, Matthew W.

AU - Georg, Gunda I.

N1 - Funding Information: We thank the National Institutes of Health for their generous support of our programs (NIH CA90602, NIH GM076302, and NIH GM069663). B.J.T. was supported by the Department of Defense Breast Cancer Predoctoral Fellowship (DAMD17-02-1-0435).

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Microwave-assisted Suzuki-Miyaura couplings on α-iodoenaminones

Abstract

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