Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals

Sharon B. Mannheimer; Nicholas Wold; Edward M. Gardner; Edward E. Telzak; Katherine Huppler Hullsiek; Margaret Chesney; Albert W. Wu; Rodger D. MacArthur; John Matts; Gerald Friedland

doi:10.1086/528859

Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals

Sharon B. Mannheimer, Nicholas Wold, Edward M. Gardner, Edward E. Telzak, Katherine Huppler Hullsiek, Margaret Chesney, Albert W. Wu, Rodger D. MacArthur, John Matts, Gerald Friedland

Biostatistics

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Abstract

Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life. Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline.

Original language	English (US)
Pages (from-to)	941-945
Number of pages	5
Journal	Clinical Infectious Diseases
Volume	46
Issue number	6
DOIs	https://doi.org/10.1086/528859
State	Published - Mar 15 2008

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Funding Information:
Financial support. The National Institute of Allergy and Infectious Diseases, National Institutes of Health (5U01AI042170-10 and 5U01AI046362-03) provided financial support for this work by the Community Programs for Clinical Research on AIDS Adherence Working Group as part of the FIRST study (CPCRA 058). Potential conflicts of interest. All authors: no conflicts.

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title = "Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals",

abstract = "Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life. Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline.",

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AU - Huppler Hullsiek, Katherine

AU - Chesney, Margaret

AU - Wu, Albert W.

AU - MacArthur, Rodger D.

AU - Matts, John

AU - Friedland, Gerald

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Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals

Abstract

Bibliographical note

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