Mitosis, diffusible crosslinkers, and the ideal gas law

David J. Odde

doi:10.1016/j.cell.2015.02.048

Mitosis, diffusible crosslinkers, and the ideal gas law

David J. Odde

Biomedical Engineering

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

During mitosis, molecular motors hydrolyze ATP to generate sliding forces between adjacent microtubules and form the bipolar mitotic spindle. Lansky et al. now show that the diffusible microtubule crosslinker Ase1p can generate sliding forces between adjacent microtubules, and it does so without ATP hydrolysis.

Original language	English (US)
Pages (from-to)	1041-1043
Number of pages	3
Journal	Cell
Volume	160
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2015.02.048
State	Published - Mar 15 2015

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© 2015 Elsevier Inc.

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title = "Mitosis, diffusible crosslinkers, and the ideal gas law",

abstract = "During mitosis, molecular motors hydrolyze ATP to generate sliding forces between adjacent microtubules and form the bipolar mitotic spindle. Lansky et al. now show that the diffusible microtubule crosslinker Ase1p can generate sliding forces between adjacent microtubules, and it does so without ATP hydrolysis.",

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Mitosis, diffusible crosslinkers, and the ideal gas law

Abstract

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