Modeling the repetitive firing of retinal ganglion cells

J. F. Fohlmeister; P. A. Coleman; Robert F Miller

doi:10.1016/0006-8993(90)91388-W

Modeling the repetitive firing of retinal ganglion cells

J. F. Fohlmeister, P. A. Coleman, Robert F Miller

Neuroscience

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

A kinetic model for the repetitive firing of retinal ganglion cells were synthesized from voltage-clamp data and evaluated by comparison with whole cell recordings from ganglion cells in the intact tiger salamander retina. Five distinct channels were included in the model and were sufficient to describe the physiologically observed frequency/current relationship in response to various levels of cell depolarization.

Original language	English (US)
Pages (from-to)	343-345
Number of pages	3
Journal	Brain Research
Volume	510
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(90)91388-W
State	Published - Mar 5 1990

Keywords

Channel kinetics
Computer modelling
Ganglion cell
Ion channel
Repetitive firing
Retina

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abstract = "A kinetic model for the repetitive firing of retinal ganglion cells were synthesized from voltage-clamp data and evaluated by comparison with whole cell recordings from ganglion cells in the intact tiger salamander retina. Five distinct channels were included in the model and were sufficient to describe the physiologically observed frequency/current relationship in response to various levels of cell depolarization.",

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KW - Ion channel

KW - Repetitive firing

KW - Retina

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Modeling the repetitive firing of retinal ganglion cells

Abstract

Keywords

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