ModVis: An information visualization tool for gene module discovery

Justin Molineaux, Jianhua Xuan, Ting Gong, Yitan Zhu, Eric Hoffman, Robert Clarke, Yue Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The repeated grouping of genes across module sets produced by different module discovery methods may prove to be biologically significant in the area of functional genomics. To ease in the exploration of these overlapping groups of genes, we introduce ModVis, a software tool that allows for the interactive visualization of module discovery data, with an emphasis on the overlap between data sets derived from different methods. Our tool provides a high-level overview of multiple module sets, displaying the modules in each set, and the location and magnitude of the overlap between sets. The tool's more-detailed visualization displays a heat map for a particular gene module, and organizes the heat maps for its overlapping modules so that the individual genes involved in the overlap become readily apparent.

Original languageEnglish (US)
Title of host publication19th International Conference on Computer Applications in Industry and Engineering, CAINE 2006
Pages24-31
Number of pages8
StatePublished - 2006
Externally publishedYes
Event19th International Conference on Computer Applications in Industry and Engineering, CAINE 2006 - Las Vegas, NV, United States
Duration: Nov 13 2006Nov 15 2006

Publication series

Name19th International Conference on Computer Applications in Industry and Engineering, CAINE 2006

Conference

Conference19th International Conference on Computer Applications in Industry and Engineering, CAINE 2006
CountryUnited States
CityLas Vegas, NV
Period11/13/0611/15/06

Keywords

  • Gene clustering
  • Gene regulatory networks
  • Information visualization

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