Multicomponent obesity prevention intervention in low-income preschoolers: Primary and subgroup analyses of the NET-works randomized clinical trial, 2012-2017

Simone A French, Nancy E Sherwood, Sara Veblen-Mortenson, A. Lauren Crain, Meghan M. JaKa, Nathan Mitchell, Anne Marie Hotop, Jerica M Berge, Alicia S Kunin-Batson, Kim Truesdale, June Stevens, Charlotte Pratt, Layla Esposito

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40 Scopus citations

Abstract

Objectives. To evaluate a multicomponent obesity prevention intervention among diverse, low-income preschoolers. Methods. Parent-child dyads (n = 534) were randomized to the Now Everybody Together for Amazing and Healthful Kids (NET-Works) intervention or usual care in Minneapolis, MN (2012-2017). The intervention consisted of home visits, parenting classes, and telephone check-ins. The primary outcomes were adjusted 24- and 36-month body mass index (BMI). Results. Compared with usual care, the NET-Works intervention showed no significant difference in BMI change at 24 (-0.12 kg/m2; 95% confidence interval [CI] = -0.44, 0.19) or 36 months (-0.19 kg/m2; 95% CI = -0.64, 0.26). Energy intake was significantly lower in the NET-Works group at 24 (-90 kcal/day; 95% CI = -164, -16) and 36 months (-101 kcal/day; 95% CI = -164, -37). Television viewing was significantly lower in the NET-Works group at 24 (rate ratio = 0.84; 95% CI = 0.75, 0.93) and 36 months (rate ratio = 0.88; 95% CI = 0.78, 0.99). Children with baseline overweight or obesity had lower BMI in the NET-Works group than those in usual care at 36 months (-0.71 kg/m2; 95% CI = -1.30, -0.12). Hispanic children had lower BMI in the NET-Works group than those in usual care at 36 months (-0.59 kg/m2; 95% CI = -1.14, -0.04). Conclusions. In secondary analyses, NET-Works significantly reduced BMI over 3 years among Hispanic children and children with baseline overweight or obesity. Trial Registration: ClinicalTrials.gov Identifier: NCT01606891.

Original languageEnglish (US)
Pages (from-to)1695-1706
Number of pages12
JournalAmerican journal of public health
Volume108
Issue number12
DOIs
StatePublished - Dec 2018

Bibliographical note

Funding Information:
This research was supported by award U01HD068990, with additional support from other members of Childhood Obesity Prevention and Treatment Research Consortium (awards U01HL103622, U01HL103629, U01HL103620, U01HL103561) from the National Heart, Lung, and Blood Institute; the Eunice Kennedy Shriver National Institute of Child Health and Human Development; and the Office of Behavioral and Social Sciences Research, National Institutes of Health.

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