This study investigated the cross-cultural similarity of vocational interests. Mexican and U.S. male law and engineering students and U.S. male professional engineers and lawyers (N = 814) were tested using the English or validated Spanish form of the Strong-Campbell Interest Inventory (SCII). Multiple discriminant function analyses were used to investigate the cross-cultural similarity of vocational interests of engineers and lawyers. Results indicated that all groups were significantly different (p ≤ .05) but that group centroids of Mexican and U.S. student engineers were closer than were group centroids for U.S. and Mexican student lawyers. The results are discussed with implications for cross-cultural interpretations of the SCII.