Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice

Christopher J. Cummings, Eyal Reinstein, Sun Yaling, Barbara Antalffy, Yong Hui Jiang, Aaron Ciechanover, Harry T. Orr, Arthur L. Beaudet, Huda Y. Zoghbi

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424 Scopus citations

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Medicine & Life Sciences