TY - JOUR
T1 - Mycobacterial infection after liver transplantation
T2 - A report of three cases and review of the literature
AU - Sterneck, M.
AU - Ferrell, L.
AU - Ascher, N.
AU - Roberts, J.
AU - Lake, J. R.
PY - 1992/1/1
Y1 - 1992/1/1
N2 - We report 3 cases of tuberculosis occurring after liver transplantation. Two patients presented with fever, 2 and 8 months after transplantation, while the third patient was asymptomatic. In the first case, disseminated disease developed rapidly; the other 2 patients presented with pulmonary disease only. In all patients the mycobacterial infection was treated with INH, rifampin and pyrazinamide, as well as ethambutol in the first case. Anti-tuberculous treatment was complicated in the first case by development of severe INH hepatitis after 9 months, necessitating drug withdrawal. The prophylaxis, diagnosis and treatment of mycobacterial infections in liver transplant recipients are discussed.
AB - We report 3 cases of tuberculosis occurring after liver transplantation. Two patients presented with fever, 2 and 8 months after transplantation, while the third patient was asymptomatic. In the first case, disseminated disease developed rapidly; the other 2 patients presented with pulmonary disease only. In all patients the mycobacterial infection was treated with INH, rifampin and pyrazinamide, as well as ethambutol in the first case. Anti-tuberculous treatment was complicated in the first case by development of severe INH hepatitis after 9 months, necessitating drug withdrawal. The prophylaxis, diagnosis and treatment of mycobacterial infections in liver transplant recipients are discussed.
KW - Isoniazid
KW - Liver transplantation
KW - Mycobacterial infection
KW - Rifampin
UR - http://www.scopus.com/inward/record.url?scp=0026560347&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026560347&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0026560347
SN - 0902-0063
VL - 6
SP - 55
EP - 61
JO - Clinical Transplantation
JF - Clinical Transplantation
IS - 1
ER -
