Nanobiocatalysis, in which enzymes are incorporated into nanostructured materials, has emerged as a rapidly growing area. Nanostructures, including nanoporous media, nanofibers, carbon nanotubes and nanoparticles, have manifested great efficiency in the manipulation of the nanoscale environment of the enzyme and thus promise exciting advances in many areas of enzyme technology. This review will describe these recent developments in nanobiocatalysis and their potential applications in various fields, such as trypsin digestion in proteomic analysis, antifouling, and biofuel cells.
Bibliographical noteFunding Information:
Parts of this work were supported by a Korea Research Foundation Grant funded by the Korean Government (MOEHRD, Basic Research Promotion Fund) [KRF-2007–313-D00152]. We appreciate S-H. Jun and B. Lee for their help in the preparation of figures. J.W.G. acknowledges the William R. Wiley Environmental Molecular Sciences Laboratory, a US Department of Energy (DOE) scientific user facility operated for the DOE by the Pacific Northwest National Laboratory (PNNL). The PNNL is a multiprogram national laboratory operated for the US DOE by the Battelle Memorial Institute.