Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity

Earth & Environmental Sciences

• infectivity 100%
• human immunodeficiency virus 91%
• polymorphism 77%
• mutation 72%
• protein 52%
• virus 26%
• gene 20%
• infection 17%
• phenotype 9%
• half life 9%
• amino acid 8%
• DNA 7%
• fold 6%
• family 6%
• degradation 5%

Medicine & Life Sciences

• HIV-1 63%
• vif Gene Products 51%
• T-Lymphocytes 45%
• Haplotypes 41%
• Mutation 40%
• Virus Replication 29%
• Human immunodeficiency virus 1 vif protein 27%
• Proteins 26%
• Cytosine Deaminase 22%
• vif Genes 21%
• Lymphocytes 20%
• Viral Genes 17%
• Half-Life 12%
• HIV Infections 12%
• Antiviral Agents 12%
• Genes 11%
• Amino Acids 10%
• Viruses 9%
• Pressure 9%
• Phenotype 8%
• DNA 8%
• Infections 6%

Agriculture & Biology

• Human immunodeficiency virus 1 89%
• T-lymphocytes 66%
• pathogenicity 58%
• genetic polymorphism 53%
• mutation 49%
• proteins 24%
• haplotypes 23%
• virus replication 20%
• cytosine deaminase 15%
• lymphocytes 15%
• infection 9%
• genes 9%
• half life 8%
• phenotype 6%
• viruses 5%
• degradation 5%
• amino acids 5%
• DNA 4%