Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter

Medicine & Life Sciences

• ATP-Binding Cassette Transporters 100%
• Respiratory Insufficiency 79%
• Lipids 55%
• Mutation 47%
• Pulmonary Surfactants 33%
• Surfactant Dysfunction 20%
• Paternal Inheritance 17%
• Maternal Inheritance 15%
• RNA Splice Sites 15%
• Loss of Function Mutation 13%
• Alveolar Epithelial Cells 13%
• Surface-Active Agents 12%
• Cell Body 12%
• Computer Simulation 11%
• Newborn Infant 9%
• Parturition 8%
• Transplants 7%

Chemical Compounds

• Mutation 71%
• Lipid 57%
• Surfactant 56%