Neutrophil leukocyte reserves in lymphoreticular malignancies

Ignacio E. Fortuny; Athanasios Theologides; Daniel C. Hadlock; B. J. Kennedy; Amos Deinard

doi:10.1002/mpo.2950020206

Neutrophil leukocyte reserves in lymphoreticular malignancies

Ignacio E. Fortuny, Athanasios Theologides, Daniel C. Hadlock, B. J. Kennedy, Amos Deinard

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Abstract

The marginal neutrophil leukocyte pool and the bone marrow neutrophil reserves were assessed in 43 patients with lymphoreticular malignancies, using epinephrine and steroid stimulation. Thirty‐three patients were studied before staging, following splenectomy, before and after nodal irradiation and during remission induction chemotherapy. Ten patients in partial remission were studied after 12 months or more of chemotherapy. A neutrophil count of 1,500–2,500 cells/mm³ is not a sufficient guide for modifying the chemotherapy. The response to steroid stimulation may be a more dependable guide to evaluate the patient's potential risk for infection.

Original language	English (US)
Pages (from-to)	167-172
Number of pages	6
Journal	Medical and Pediatric Oncology
Volume	2
Issue number	2
DOIs	https://doi.org/10.1002/mpo.2950020206
State	Published - 1976

Keywords

Hodgkin's
lymphoma
neutrophils

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title = "Neutrophil leukocyte reserves in lymphoreticular malignancies",

abstract = "The marginal neutrophil leukocyte pool and the bone marrow neutrophil reserves were assessed in 43 patients with lymphoreticular malignancies, using epinephrine and steroid stimulation. Thirty‐three patients were studied before staging, following splenectomy, before and after nodal irradiation and during remission induction chemotherapy. Ten patients in partial remission were studied after 12 months or more of chemotherapy. A neutrophil count of 1,500–2,500 cells/mm3 is not a sufficient guide for modifying the chemotherapy. The response to steroid stimulation may be a more dependable guide to evaluate the patient's potential risk for infection.",

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AU - Theologides, Athanasios

AU - Hadlock, Daniel C.

AU - Kennedy, B. J.

AU - Deinard, Amos

PY - 1976

Y1 - 1976

N2 - The marginal neutrophil leukocyte pool and the bone marrow neutrophil reserves were assessed in 43 patients with lymphoreticular malignancies, using epinephrine and steroid stimulation. Thirty‐three patients were studied before staging, following splenectomy, before and after nodal irradiation and during remission induction chemotherapy. Ten patients in partial remission were studied after 12 months or more of chemotherapy. A neutrophil count of 1,500–2,500 cells/mm3 is not a sufficient guide for modifying the chemotherapy. The response to steroid stimulation may be a more dependable guide to evaluate the patient's potential risk for infection.

AB - The marginal neutrophil leukocyte pool and the bone marrow neutrophil reserves were assessed in 43 patients with lymphoreticular malignancies, using epinephrine and steroid stimulation. Thirty‐three patients were studied before staging, following splenectomy, before and after nodal irradiation and during remission induction chemotherapy. Ten patients in partial remission were studied after 12 months or more of chemotherapy. A neutrophil count of 1,500–2,500 cells/mm3 is not a sufficient guide for modifying the chemotherapy. The response to steroid stimulation may be a more dependable guide to evaluate the patient's potential risk for infection.

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KW - lymphoma

KW - neutrophils

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Neutrophil leukocyte reserves in lymphoreticular malignancies

Abstract

Keywords

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