New Materials for Biotechnology: Chromatographic Stationary Phases Based on Zirconia

Jacek Nawrocki; Christopher J. Dunlap; Peter W. Carr; John A. Blackwell

doi:10.1021/bp00030a001

New Materials for Biotechnology: Chromatographic Stationary Phases Based on Zirconia

Jacek Nawrocki, Christopher J. Dunlap, Peter W. Carr, John A. Blackwell

Chemistry (Twin Cities)

Research output: Contribution to journal › Review article › peer-review

82 Scopus citations

Abstract

This review explores the usefulness of zirconia‐based materials in separations in biotechnology. The physical and chemical properties of zirconia are discussed briefly to familiarize the reader with the advantages of zirconia. The use of native zirconia is then examined, with a study of the Lewis acid/base chemistry that defines chromatography with zirconia. Modification of the zirconia surface with small molecules is then discussed. Finally, polymer‐coated zirconia materials are examined. Examples of separations using these various materials are shown. The advantages and disadvantages of each of these materials are presented.

Original language	English (US)
Pages (from-to)	561-573
Number of pages	13
Journal	Biotechnology Progress
Volume	10
Issue number	6
DOIs	https://doi.org/10.1021/bp00030a001
State	Published - 1994

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title = "New Materials for Biotechnology: Chromatographic Stationary Phases Based on Zirconia",

abstract = "This review explores the usefulness of zirconia‐based materials in separations in biotechnology. The physical and chemical properties of zirconia are discussed briefly to familiarize the reader with the advantages of zirconia. The use of native zirconia is then examined, with a study of the Lewis acid/base chemistry that defines chromatography with zirconia. Modification of the zirconia surface with small molecules is then discussed. Finally, polymer‐coated zirconia materials are examined. Examples of separations using these various materials are shown. The advantages and disadvantages of each of these materials are presented.",

author = "Jacek Nawrocki and Dunlap, {Christopher J.} and Carr, {Peter W.} and Blackwell, {John A.}",

year = "1994",

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journal = "Biotechnology Progress",

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AU - Carr, Peter W.

AU - Blackwell, John A.

PY - 1994

Y1 - 1994

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AB - This review explores the usefulness of zirconia‐based materials in separations in biotechnology. The physical and chemical properties of zirconia are discussed briefly to familiarize the reader with the advantages of zirconia. The use of native zirconia is then examined, with a study of the Lewis acid/base chemistry that defines chromatography with zirconia. Modification of the zirconia surface with small molecules is then discussed. Finally, polymer‐coated zirconia materials are examined. Examples of separations using these various materials are shown. The advantages and disadvantages of each of these materials are presented.

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JO - Biotechnology Progress

JF - Biotechnology Progress

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ER -

New Materials for Biotechnology: Chromatographic Stationary Phases Based on Zirconia

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