Abstract
Self-assembled matrices of magnetic beads have shown their potential to separate long DNA (>100 kbp). Because of their tunability, they represent an interesting alternative to arrays of posts obtained by microlithography. In this paper, a nickel template is used to nucleate the obstacles growth and thus organize the matrix around a predefined design. DNA molecules, 48 to 166 kbp long, were separated in minutes and the measured resolution was compared to theoretical predictions.
Original language | English (US) |
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Title of host publication | Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference |
Subtitle of host publication | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Publisher | Japan Academic Association Inc |
Pages | 386-388 |
Number of pages | 3 |
State | Published - Jan 1 2006 |
Event | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan Duration: Nov 5 2006 → Nov 9 2006 |
Other
Other | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 |
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Country/Territory | Japan |
City | Tokyo |
Period | 11/5/06 → 11/9/06 |
Keywords
- DNA electrophoresis
- Magnetic beads
- Ni pattern