Ni pattern for guiding magnetic beads self-organization: Application to long DNA electrophoresis in dilute arrays

Antoine Emmanuel Saliba, Charlie Gosse, Nicolas Minc, Christophe Roblin, Kevin Dorfman, Jean Louis Viovy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Self-assembled matrices of magnetic beads have shown their potential to separate long DNA (>100 kbp). Because of their tunability, they represent an interesting alternative to arrays of posts obtained by microlithography. In this paper, a nickel template is used to nucleate the obstacles growth and thus organize the matrix around a predefined design. DNA molecules, 48 to 166 kbp long, were separated in minutes and the measured resolution was compared to theoretical predictions.

Original languageEnglish (US)
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference
Subtitle of host publication10th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherJapan Academic Association Inc
Pages386-388
Number of pages3
StatePublished - Jan 1 2006
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: Nov 5 2006Nov 9 2006

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
Country/TerritoryJapan
CityTokyo
Period11/5/0611/9/06

Keywords

  • DNA electrophoresis
  • Magnetic beads
  • Ni pattern

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