Non-Hodgkin's lymphoma in the elderly. Part 2: Treatment of diffuse aggressive lymphomas

Vicki A Morrison

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

As noted in part 1 of this two-part article, non-Hodgkin's lymphoma is one of a few malignancies that have been increasing in incidence over the past several decades. Likewise, these disorders are more common in elderly patients, with a median age of occurrence of 65 years. Therapy in elderly patients may be affected by multiple factors, especially attendent comorbidities. The approaches to management of these patients, with either indolent or aggressive disease processes, have been based on prospective clinical trial results, many of which have included a younger patient population. Fortunately over the past decade, results of treatment trials that have targeted an older patient population have emerged. The disease incidence and treatment approaches for both follicular (part 1) and diffuse aggressive (part 2) histologies in elderly patients are reviewed, as well as the impact of aging on the care of these patients.

Original languageEnglish (US)
Pages (from-to)1191-1198
Number of pages8
JournalONCOLOGY
Volume21
Issue number10
StatePublished - Sep 1 2007

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