Nonimmune hydrops fetalis and fulminant fatal disease due to congenital cytomegalovirus infection in a premature infant

Venkatesh Sampath; Vivek Narendan; Edward F. Donovan; Jerzy Stanek; Mark R. Schleiss

doi:10.1038/sj.jp.7211357

Nonimmune hydrops fetalis and fulminant fatal disease due to congenital cytomegalovirus infection in a premature infant

Venkatesh Sampath, Vivek Narendan, Edward F. Donovan, Jerzy Stanek, Mark R. Schleiss

Pediatrics - Infectious Disease

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We report a case of fatal congenital cytomegalovirus (CMV) disease in a 695gm, 29 weeks estimated gestational age premature infant. The newborn presented with hydrops fetalis, an unusual presentation of congenital CMV infection. In spite of ganciclovir therapy, the infant succumbed to his illness. Autopsy findings revealed the presence of widespread CMV disease, including pneumonitis, enteritis, and myocarditis. Congenital CMV infection should be considered in the differential diagnosis of hydrops fetalis.

Original language	English (US)
Pages (from-to)	608-611
Number of pages	4
Journal	Journal of Perinatology
Volume	25
Issue number	9
DOIs	https://doi.org/10.1038/sj.jp.7211357
State	Published - Sep 2005

Bibliographical note

Funding Information:
Helpful discussions with Tenessa MacKenzie, University of Florida School of Medicine, are acknowledged. Grant support is acknowledged for study of congenital CMV infection (NIH HD38416-01, HD44864-01, and the March of Dimes Birth Defects Foundations FY01-22).

Access

10.1038/sj.jp.7211357

OpenUrl availability

Full text

Cite this

@article{e2866f17d580434ebc15e244fb7fceca,

title = "Nonimmune hydrops fetalis and fulminant fatal disease due to congenital cytomegalovirus infection in a premature infant",

abstract = "We report a case of fatal congenital cytomegalovirus (CMV) disease in a 695gm, 29 weeks estimated gestational age premature infant. The newborn presented with hydrops fetalis, an unusual presentation of congenital CMV infection. In spite of ganciclovir therapy, the infant succumbed to his illness. Autopsy findings revealed the presence of widespread CMV disease, including pneumonitis, enteritis, and myocarditis. Congenital CMV infection should be considered in the differential diagnosis of hydrops fetalis.",

author = "Venkatesh Sampath and Vivek Narendan and Donovan, {Edward F.} and Jerzy Stanek and Schleiss, {Mark R.}",

note = "Funding Information: Helpful discussions with Tenessa MacKenzie, University of Florida School of Medicine, are acknowledged. Grant support is acknowledged for study of congenital CMV infection (NIH HD38416-01, HD44864-01, and the March of Dimes Birth Defects Foundations FY01-22).",

year = "2005",

month = sep,

doi = "10.1038/sj.jp.7211357",

language = "English (US)",

volume = "25",

pages = "608--611",

journal = "Journal of Perinatology",

issn = "0743-8346",

publisher = "Nature Publishing Group",

number = "9",

}

TY - JOUR

T1 - Nonimmune hydrops fetalis and fulminant fatal disease due to congenital cytomegalovirus infection in a premature infant

AU - Sampath, Venkatesh

AU - Narendan, Vivek

AU - Donovan, Edward F.

AU - Stanek, Jerzy

AU - Schleiss, Mark R.

N1 - Funding Information: Helpful discussions with Tenessa MacKenzie, University of Florida School of Medicine, are acknowledged. Grant support is acknowledged for study of congenital CMV infection (NIH HD38416-01, HD44864-01, and the March of Dimes Birth Defects Foundations FY01-22).

PY - 2005/9

Y1 - 2005/9

N2 - We report a case of fatal congenital cytomegalovirus (CMV) disease in a 695gm, 29 weeks estimated gestational age premature infant. The newborn presented with hydrops fetalis, an unusual presentation of congenital CMV infection. In spite of ganciclovir therapy, the infant succumbed to his illness. Autopsy findings revealed the presence of widespread CMV disease, including pneumonitis, enteritis, and myocarditis. Congenital CMV infection should be considered in the differential diagnosis of hydrops fetalis.

AB - We report a case of fatal congenital cytomegalovirus (CMV) disease in a 695gm, 29 weeks estimated gestational age premature infant. The newborn presented with hydrops fetalis, an unusual presentation of congenital CMV infection. In spite of ganciclovir therapy, the infant succumbed to his illness. Autopsy findings revealed the presence of widespread CMV disease, including pneumonitis, enteritis, and myocarditis. Congenital CMV infection should be considered in the differential diagnosis of hydrops fetalis.

UR - http://www.scopus.com/inward/record.url?scp=31044432973&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=31044432973&partnerID=8YFLogxK

U2 - 10.1038/sj.jp.7211357

DO - 10.1038/sj.jp.7211357

M3 - Article

C2 - 16123790

AN - SCOPUS:31044432973

SN - 0743-8346

VL - 25

SP - 608

EP - 611

JO - Journal of Perinatology

JF - Journal of Perinatology

IS - 9

ER -

Nonimmune hydrops fetalis and fulminant fatal disease due to congenital cytomegalovirus infection in a premature infant

Abstract

Bibliographical note

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this